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KMID : 0358419960390030498
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Korean Journal of Obstetrics and Gynecology
1996 Volume.39 No. 3 p.498 ~ p.504
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Measurement of Progesterone and Human Chorionic Gonadotropin as Predictors of Early Pregnancy Viability
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원현주
윤수정/양선이/강혜승/전선희/우복희
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Abstract
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Objective:
@EN To assess of the role of a single maternal serum progesterone measurement and serum hCG doubling time in the immediate of early pregnancy failure and in the long term prognosis of fetal viability.
@ES Study Design:
@EN A progressive comparative study of women presenting with non visible fetal heart beat by vaginal sonography during the first 49 days of gestation. The study groups were defined retrospectively as viable intrauterine pregnancy(n=36) and non
viable
intrauterine pregnancy(n=56) groups, according to the outcome of the pregnancies.
@ES Results:
@EN Receiver-operactor characteristic curve analysis indicated that the best discriminatory progesterone concentrations was 14ng/mL and hCG 1/DT(doubling time) was 0.40. When progesterone was less than 14ng/mL. The predictive value of the
abnormal
test
result was 95%. When hCG 1/DT was less than 0.4. the predictive value of the abnormal test result was 77%.
@ES Conclusions:
@EN A single serum progesterone measurement and hCG doubling times taken in the early pregnancy is valuable in the immediate diagnosis of early pregnancy failure and the long term prognosis of viability.
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KEYWORD
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